Whether the campaign is a threat or not is yet to be seen, but online petitions asking the PM to step down have increased exponentially over the last few days.
The PM's controversial policies regarding fracking, the privatisation of the NHS and the recent phone hacking scandal are amongst topics mostly discussed under the hashtag.
Many tweets condemning Cameron have been interpreted as a sense of underlying anger and injustice felt by the British public and some tweets read:
“If the Tories win the election the very fabric of Britain will be rubbed out” and “#CameronMustGo b/c I don't want to see a repeat of my youth when the solution to poverty, no health care & poor housing was the workhouse.”
Not nearly as popular, the #CameronMustStay hashtag gives Tory supporters their own space to express their opinions.
We spoke to political economist and East Sussex university graduate, Helena Takala who believed the hash tag will not affect the PM's general election campaign.
“People who support the hash tag are the people opposing him anyway, either because they are old Tory voters who are going to vote UKIP or because they – like me –would never even think of voting Tories”
With the Prime Minister's popularity seemingly tumbling down, it seems UKIP are relishing Mr Cameron's misery.
Takala also had concerns about Cameron’s empty promises :“He is privileged beyond imagination and represents corporate, financial and old money interests at the expense of the poor and the working classes in Britain”.
Whether positive or negative, the Prime Minister has certainly managed to capture the attention of the British public once again.